Skip to Main Content

 

 

Clinical Trials

Note: This document is prepared as a service for the ALS community and is intended as general information. Content used in this report is obtained from informed members of the pharmaceutical industry and the ALS community.

For further information on drug trials, ClinicalTrials.gov provides patients, family members, and members of the public easy and free access to information on clinical studies for a wide range of diseases and conditions. For an overview of clinical trials information, click here.

Open Trials

Compound or Trial Status & Sites Company or Center
A Randomized Crossover Study of standard NIPPV and low expiratory pressure NIPPV in ALS patients Current Grants Kirsten Gruis, MD, Assistant Medical Center
ALS Gene Study Enrolling University of Massachusetts Medical Center
Average Volume Assured Pressure Support (AVAPS) in ALS Patients with Nocturnal Hypoventilation: A Randomized Crossover Trial Current Grants Jonathan Katz, MD
Clinical Research on Familial ALS Enrolling
Communications Study Enrolling University of Washington
SOD1 Antisense Enrolling MGH Neurology Clinical Trial Unit
Phase 1 Stem Cell Trial Enrolling Neuralstem/Emory University
Validation of ALS Biomarkers Enrolling Multi-center
Electrical Impedence Myography Enrolling Beth Israel Deaconess
Tretinoin and Pioglitazone HCL Combination Therapy Enrolling Phoenix Neurological Associates
Major Depression in ALS Enrolling University of South Carolina
AVP-923 in PBA Patients Enrolling Multi-center
Memantine Trial Enrolling University of Alberta
Trial for Familial ALS Enrolling Emory University
New Gene Study Enrolling University of Massachusetts
Medical Center
Ceftriaxone Enrolling Northeast ALS Consortium
Arimoclomol Enrolling Emory University
High Fat/High Calorie Trial
in Amyotrophic Lateral Sclerosis
Enrolling Massachusetts General Hospital
Quality of Life Survey Enrolling Penn State College of Medicine

Closed Trials

Compound or Trial Status Company or Center
CK-2017357 Enrollment Closed Cytokinetics
Talampanel Study Completed Teva Pharmaceuticals, LTD
Tamoxifen Enrollment Closed The University of Wisconsin-Madison
Thalidomide Enrollment Closed Dartmouth-Hitchcock Medical Center
Diaphragm Training Study Completed Beth ISrael Deaconess Medical Center
National Registry of Veterans with ALS Enrollment Closed Durham, North Carolina VAMC
Combination Therapy Selection Trial in ALS Enrollment Closed Multi-center
Sodium Phenylbutyrate Enrollment Closed Multi-center
The Vest Study Completed Hill-Rom
Creatine Enrollment Closed The Carolinas Neuromuscular/ALS Center
Myotrophin Study Completed Cephalon
Celebrex Study Closed Northeast ALS Consortium
NeotrofinTM Study Closed NeoTherapeutics, Inc.
NAALADase Study Closed Guilford Pharmaceuticals Inc.
Neurodex Study Completed Avanir Pharmaceuticals
Rilutek FDA approved drug currently available Aventis S.A.
Oxandrolone Study Completed The Carolinas Neuromuscular/ALS MDA Center
Pilot CoQ10 Enrollment Closed Eleanor and Lou Gehrig ALS Center at Columbia University
High Dose Coenzyme Q10 Enrollment Closed Eleanor and Lou Gehrig ALS Center at Columbia University
Pilot CoQ10 with imaging Enrollment Closed Eleanor and Lou Gehrig ALS Center at Columbia University
Topiramate (Topamax) Study Completed North Eastern ALS Consortium
Xaliproden Preliminary analysis released 9/5/00 Sanofi-Synthelabo Inc.
Indinavir Study Completed Beth Israel Medical Center
Creatine Study Completed North Eastern ALS Consortium
Creatine Study Completed The West Virigina University School of Medicine
Minocycline Investigation Enrollment Closed Eleanor and Lou Gehrig ALS Center at Columbia University
Buspirone Investigation Study Completed Multi-center ALS
Memantine Therapy Enrollment Closed Banner Good Samaritan ALS Clinic
CL201 Study in ALS Enrollment Closed Multi-center
Talampanel Enrollment Closed Teva Pharmaceuticals, LTD
Lithium Study Completed Multi-center
 

 



ABOUT SSL CERTIFICATES

All content and works posted on this website are owned and copyrighted by The ALS Association. ©2014
Contact the Webmaster